
TB-500 (Thymosin Beta-4) is a synthetic 43-amino acid peptide corresponding to the active region of the naturally occurring thymic protein currently being studied for its interactions with actin-modulating and angiogenesis pathways in controlled laboratory settings. This compound is supplied exclusively for scientific research and is not approved for human or animal consumption.
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TB-500 (Thymosin Beta-4) is a synthetic 43-amino acid peptide corresponding to the active region of the naturally occurring thymic protein currently being studied for its interactions with actin-modulating and angiogenesis pathways in controlled laboratory settings. This compound is supplied exclusively for scientific research and is not approved for human or animal consumption.
Laboratory: Freedom Diagnostics (USA)
Principal Chemist: Stephen Schmidt
Methods: HPLC with UV Detection + LCMS/MS
Result: 99.883% purity verified
Every lot ships with a published COA documenting purity, identity, and verified peptide content.
Download COA (PDF)TB-500, corresponding to Thymosin Beta-4 (Tβ4), is a synthetic peptide modeled on the naturally occurring 43-amino acid thymic protein first isolated from calf thymus tissue. As a synthetic Thymosin Beta-4 analogue, TB-500 is among the more extensively studied peptides in experimental biology, with a substantial body of preclinical literature exploring its interactions with G-actin sequestration, cell migration signaling, and vascular biology mechanisms.
Current research investigates TB-500 across a range of biological systems, including endothelial cell models, actin dynamics studies, angiogenesis pathway research, and connective tissue biology investigations. Studies conducted in controlled laboratory settings suggest notable activity in actin-binding interactions and downstream cell migration signaling, making it a compound of significant interest in cytoskeletal and vascular biology research.
21 Peptide™ supplies TB-500 exclusively for scientific research purposes. This compound is not approved for human or animal consumption and is not intended for diagnostic, therapeutic, or clinical use.
CAS NO: 77591-33-4
Molecular Formula: C₂₁₂H₃₅₀N₅₆O₇₈S
Molecular Weight: 4963 g/mol
Appearance: White powder
Storage: 2-8°C
Quality Control
Lot Number: 21P-TB500-2602-CLR
Purity: 99.883%
Verified Peptide Content: 5.54 mg
Testing Method: HPLC with UV Detection + LCMS/MS
Testing Laboratory: Freedom Diagnostics
> Search Code: 21Pe2602230196
Analytical Verification
Identity Confirmation: Mass spectrometry confirms the molecular structure of Thymosin Beta-4 (TB-500).
Chromatographic Analysis: HPLC chromatogram verifies peptide purity and separation profile.
Testing Method:
- High-Performance Liquid Chromatography (HPLC)
- Mass Spectrometry (LCMS/MS)
Laboratory:
- Freedom Diagnostics - USA
- Principal Chemist: Stephen Schmidt